Evaluation of the social, clinical and laboratorial profile of patients diagnosed with leprosy in a reference center in São Paulo
AUTOR(ES)
Porto, Ana Carolina Souza, Figueira, Renata Borges Fortes Costa, Barreto, Jaison Antônio, Lauris, José Roberto Pereira
FONTE
An. Bras. Dermatol.
DATA DE PUBLICAÇÃO
2015-04
RESUMO
BACKGROUND: Leprosy is the main infectious cause of disability. It is said to be eradicated in São Paulo since 2005, but diagnosis is still late. OBJECTIVES: To investigate the social, clinical and laboratorial profile of leprosy patients diagnosed between 01/2007 and 12/2011, in a reference center in São Paulo. METHODS: Retrospective descriptive study. Data of all new leprosy cases diagnosed between 01/2007 and 12/2011 were raised in São Paulo. RESULTS: 103 men and 71 women were diagnosed, most of them were multibacillary. Mean age at diagnosis was 49 yrs; 2,2% were children; 70% had incomplete primary education; 50% were referred without diagnostic suspicion of leprosy. Mean time since first symptoms/signs and diagnosis was 2 years; 64% of patients had some degree of disability, and 26% had grade 2. 23 cases were diagnosed only after being summoned, and 80% of these had no disability. Agreement between the Ridley and Jopling and the WHO classification was 75% (kappa index = 0.44). Serology for IgM anti-PGL1 (87 patients) showed a mean value of 0.25, and an association between MB classification and test positivity (p <0.001). CONCLUSIONS: Leprosy diagnosis in São Paulo is late. The disease mainly affected the socially disadvantaged and economically active population. Failure to detect the disease (41% in the last 10 years) could be due to the lack of suspicion and to decentralization. For the classification of patients with advanced leprosy, both the WHO and R&J classifications proved to be helpful tools.
Documentos Relacionados
- Analysis of clinical aspects of leprosy patients between 2010-2017 at a reference center in Campinas,
- Histopathological profile of patients diagnosed with malignant tumors assisted in a hospital of reference of Agreste Pernambucano
- Clinical, epidemiological and therapeutic profile of patients with brachioradial pruritus in a reference service in dermatology
- Epidemiological, neurofunctional profile and prevalence of factors associated with the occurrence of physical disabilities due to leprosy in a reference center in Northeast Brasil: a sectional study
- Hidradenitis suppurativa: epidemiological study of cases diagnosed at a dermatological reference center in the city of Bauru, in the Brazilian southeast State of São Paulo, between 2005 and 2015