Evaluation of meso-substituted cationic corroles as potential antibacterial agents
AUTOR(ES)
CARDOTE, TERESA A.F., BARATA, JOANA F.B., AMADOR, CAROLINA, ALVES, ELIANA, NEVES, MARIA GRAÇA P.M.S., CAVALEIRO, JOSÉ A.S., CUNHA, ÂNGELA, ALMEIDA, ADELAIDE, FAUSTINO, MARIA AMPARO F.
FONTE
An. Acad. Bras. Ciênc.
DATA DE PUBLICAÇÃO
2018
RESUMO
ABSTRACT Cationic derivatives of 5,10,15-tris[4-(pyridin-4-ylsulphanyl)-2,3,5,6-tetrafluorophenyl]-corrolategallium(III)pyridine and 5,10,15-tris[4-(pyridin-2-ylsulfanyl)-2,3,5,6-tetrafluorophenyl]-correlategallium(III)pyridine were synthesized and their photosensitizing properties against the naturally bioluminescent Gram-negative bacterium Allivibrio fischeri were evaluated. The cationic corrole derivatives exhibited antibacterial activity at micromolar concentrations against this Gram-negative bacterium strain.
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