Estudos químicos e biológicos de Microgramma vacciniifolia (Langsd. & Fisch.) Copel (Polypodiaceae)

AUTOR(ES)

Peres, Marize T. L. P., Simionatto, Euclésio, Hess, Sônia C., Bonani, Vanderléa F. L., Candido, Ana C. S., Castelli, Caroline, Poppi, Nilva R., Honda, Neli K., Cardoso, Cláudia A. L., Faccenda, Odival

FONTE

Química Nova

DATA DE PUBLICAÇÃO

2009

RESUMO

Chemical studies with aerial parts of Microgramma vacciniifolia (Langsd. & Fisch.) Copel. afforded ²-sitosterol, hopan-22-ol, 6-metoxiapinenin-7-O-²-D-allopyranoside and a mixture containing ethyl esters of carboxilic acids. The structures of the coumpounds were elucidated by spectroscopy and GC-MS analysis. The total phenolics contents of the crude extract and fractions were determined by Folin-Ciocalteau method. The antioxidant activity was evaluated using the 2,2-diphenyl-1-picrylhydrazyl (DPPH). The AcOEt fraction showed better activity in DPPH assay (9.9 ± 0.03 µg/mL), and presented also higher contents of the total phenolic (93.60 ± 1.11 µg/mg). Antimicrobial and allelopathic effects of the crude etanolic extract and fractions also were evaluated. In addition, the combination of biological activities was discussed.

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