Estudos dos pigmentos visuais de macaco-prego (cebus sp) e da relação entre a psicofísica e a genética da visão de cores em humanos / Study of the visual pigments from capuchin monkey (Cebus sp) and the psychophysics and the genetics colour vision relationship in humans

AUTOR(ES)
DATA DE PUBLICAÇÃO

2011

RESUMO

Color vision is possible due to different types of photoreceptors and to the post receptoral processing of the information generated after cell activation by the light. Genetic, functional and morphological analysis can be used as tools in the color vision studies. In the present work the genetic of the visual pigments from Cebus sp and the genetic and the psychophysics of normal and defective human color vision were evaluated. The sequencing of the L and M genes of 33 capuchin monkeys was performed. Blood samples were collected from 13 monkeys from Instituto de Biofísica Carlos Chagas Filho (UFRJ) and 20 monkeys from Escola de Primatas (UFPA), the DNA was extracted and exons 3 and 5 from L/M genes were sequenced after PCR amplification. For each animal the 180, 277 and 285 aminoacids were identified and the spectral absorbance curve was estimated based on their sequence. In the UFRJ group, six males and three females were identified as dichromats and four females were identified as thrichromats. In the UFPA group sixteen males and three females were dichromats and one female was thrichromat. The SFT aminoacid combination was described for the first time in the Cebus genera. The allelic diversity described in these animals is probably due to the distinct environmental conditions from the place of birth of the animals. In the human study 19 control subjects (5 men and 14 women) and sixteen daltonic subjects (14 men and 1 woman), all from São Paulo city, had the colour vision evaluated with 4 colour vision tests and with the visual pigment genetics. The results were compared to the data described by Gonçalves (2006) in daltonic subjects from Pará state. The correlation between phenotype and genotype of the subjects from SP had a 100% of correspondence in the genetic and psychophysical classifications of dischromatopsia

ASSUNTO(S)

capuchin monkeys animal visual pigments genética genetics macaco-prego percepção visual pigmentos visuais em animais psicofísica psychophysics visual perception

ACESSO AO ARTIGO

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