Estudo metabólico-nutricional em alcoólatras crônicos submetidos a dietas enterais quimicamente definidas / Metabolic and nutritional effects of enteral diets on chronic alcoholic patients

AUTOR(ES)
FONTE

IBICT - Instituto Brasileiro de Informação em Ciência e Tecnologia

DATA DE PUBLICAÇÃO

03/08/1981

RESUMO

The objective of this research was to determine the utilization of nitrogen from chemically defined enteral diets ( ED), compared with oral diets, by groups of chronic alcoholic patients. The effect of ED on the recovery of nutritional status by the patients was also determined. The methods used were metabolic nitrogen balance ( WE ) and amino acid analysis of venous blood. The study was done on 20 males, If range 25-64 years ( mean age = 39,5). The subjects ( 15 White and 5 non-White individuals) ware divided at into 3 croups of 7, 7 and 6 patients, respectively. All were chronic al coholics, whose mean daily intake was 1 liter of sugar cane liquor. Seven of the patients were diagnosed as having pellagra, 5 as having peripheral neuropathy, and 1 cirrhosis of the liver. Another patient had ascites. Two patients showed 20 to 30 %. bromosulfalein retention, and 2 more showed 10 to 20 %, while the -remainder had less than MID retention. Nutritionally , these individuals were classified as low risk accoreiiny to Sauberlich .et al., 1974. The first 2 groups were offered chemically defined cntcral diets, while the third group received a usual general diet. The amount of nitrogen ( ± 16 g/day) and of calories ( 3000 cal/day) was kept constant for all groups. The calories offered to the first group consisted solely of carbohydrate and protein, without lipids. The two remaining groups received a balanced diet, with calories distribute as approximately follows: 10% protein, 65% carbohydrate and 25% fat. The .EDs consisted basically of a solution of L-amino acids, sucrose, vitamins and rninerals, with without lipide.The general diet include rice, beans meat and legumes or vegetables. The patients were admitte to the Metabolic unit of the Discipline of Nutroloyy, Department of Internal Medicine, Faculty of Medicine of Ribeirao Preto, where they remained far 15 days, 12 of which devoted to the study, The initial period of adaptation to the environment and diet lasted 6 days. During the final 6 days, all ingested nitrogen as well as fecal and urinary nitrogen were measured and the metabolic nitrogen balance was calculated. The levels of peripheral venous amino acids were measured for each patient upon admission and at discharge. The amount of absorbed nitrogen in relation to ingested nitrogen and the true gestibility of the three diets were also calculated. The following main observations were made: 1. Nutrient intake was kept constant for the patients submitted to the two enteral diets, whereas this was not possible for the third group which received the oral diet. 2. Absorption of the enteral diets WQS significantly higher than that of the oral diet. 3. The weight and amount of fecal nitrogen were significantly 6 lower for the individuals submitted to the enteral diets. 4. True digestibility was statistically higher for the enteral diets. 5. The two enteral diets gave equal results. 6. At the end of the study, a tendency towards improvement was observed for all anthropometric and laboratory parameters used to evaluate nutritional status. No differences were observed axons the patients who received the three diets. 7. No differences in plasma amino acids upon admission and at discharge were found among the three groups. 8. The enteral diets used are easy to administer and to control, and produced no problems or undesirable side effects..

ASSUNTO(S)

alcoholism desnutrição e alcoolismo malnutrition nutrição nutrition

ACESSO AO ARTIGO

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