Estudo de efeitos não termicos da radiação laser em tecidos vivos
AUTOR(ES)
Monica Alonso Cotta
DATA DE PUBLICAÇÃO
1987
RESUMO
In this work, our objective is giving physical ideas about several functional biological effects related to the irradiation of live tissues with low power lasers, which we called non-thermal effects. Due to the diversity of wavelengths and energy densities these effects have been previously observed with, we propose that the coherence of the used radiation was an Important factor in this process. To test the validity of this hypothesis, we divided the work in two parts, one experimental and one theoretical. In the experimental part, we constructed a device which permitted the irradiation of lesions artificially created on the back of rats by an He-Ne laser, or - putting a moving ground glass in the path of the laser beam, by radiation of this same laser with its coherence degree decreased. By observation of the lesions cicatrization, our test showed that the coherence of the radiation is relevant in the process and pointed to the necessity of more detailed studies in this area. From the theoretical viewpoint, we performed a study about the electrical field and intensity distribution over a surface with micro-roughness when irradiated by coherent light. In our opinion, this kind of distribution might occur in cellular surfaces and influence decisively the cell physiology, which is to a great extent controlled by electrical phenomena at the membrane level
ASSUNTO(S)
ACESSO AO ARTIGO
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