Epidermal Growth Factor: High and Low Molecular Weight Forms
AUTOR(ES)
Taylor, John M.
RESUMO
In crude homogenates of the submaxillary gland of the male mouse, epidermal growth factor (EGF) activity was found almost entirely in a high molecular weight complex (about 74,000 daltons). This high molecular weight form may be reversibly dissociated into EGF and an EGF-binding protein. EGF was found to have a molecular weight of approximately 6400. The EGF-binding protein has a molecular weight of 29,000, and shows arginyl-esterase activity.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=283183Documentos Relacionados
- Murine epidermal growth factor: heterogeneity on high resolution ion-exchange chromatography.
- Two forms of murine epidermal growth factor: rapid separation by using reverse-phase HPLC.
- THE NERVE GROWTH FACTOR: PURIFICATION AS A 30,000-MOLECULAR-WEIGHT PROTEIN*
- Human epidermal growth factor: isolation and chemical and biological properties.
- Epidermal growth factor: Biological activity requires persistent occupation of high-affinity cell surface receptors