Encapsulation of flaxseed oil extract in alginate-salep system by ionic gelation

AUTOR(ES)

Wissam, Zam

FONTE

Braz. J. Pharm. Sci.

DATA DE PUBLICAÇÃO

20/12/2019

RESUMO

The objective of the current study was to encapsulate flaxseed oil extracted from finely grounded flaxseed powder and determined for its fatty acids content by GC/FID. Ionotropic gelation method was used to form beads containing 40% flaxseed oil with vitamin E being used as an antioxidant agent. The study employed calcium chloride solution as crosslinking agent with a combination of sodium alginate and salep. The effect of polymer concentrations and calcium chloride concentration on the morphology, entrapment efficiency and oil release was studied. The encapsulation efficiency reached 93.46 ± 0.064% using 0.6% of salep and 2% sodium alginate with 0.3M calcium chloride gelling solution. In SGF medium, the matrix released only about 28.56% of the entrapped flaxseed oil after 2 hours. The rest of the oil then released in the SIF medium, continuing for up to 5 h to release 99.32% of the oil.

Documentos Relacionados

• Encapsulation of Lactobacillus acidophilus and different prebiotic agents by external ionic gelation followed by freeze-drying
• Encapsulation of blackberry anthocyanins by thermal gelation of curdlan
• Production and characterization of alginate-starch-chitosan microparticles containing stigmasterol through the external ionic gelation technique
• Encapsulation and release characteristics of glibenclamide loaded calcium-alginate beads
• Production and characterization of nanocapsules encapsulated linalool by ionic gelation method using chitosan as wall material