Elevated adjuvanticity of non-acid-fast mycobacteria.
AUTOR(ES)
Kondo, Y
RESUMO
Administration to guinea pigs of non-acid-fast (NAF) Mycobacterium avium resulted in a sevenfold greater circulating antibody response than that for the animals receiving ovalbumin in Freund incomplete adjuvant alone. The ability of NAF M. avium on induction of delayed hypersensitivity was comparable or somewhat stronger than that of normal M. avium. The in vivo enhancement of circulating antibody response by NAF M. avium associated with a marked stimulating effect of it on proliferation of B cells in regional sites. Induction of local granuloma at the injection site of NAF M. avium was less than that induced by injection of normal M. avium. Phagocytic activity of the reticuloendothelial system in mice was also greatly increased by administration of NAF M. avium.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=414568Documentos Relacionados
- Relative Susceptibility of Acid-Fast and Non-Acid-Fast Bacteria to Ultraviolet Light
- Immunological Method to Differentiate Between Antigens of Tubercle Bacilli, Other Mycobacterial Species, and Non-Acid-Fast Bacteria
- Some Artifacts Encountered in Stained Preparations of Tubercle Bacilli: I. Non-Acid-fast Forms Arising From Mechanical Treatment
- Isolation of deoxyribonucleic acid from mycobacteria.
- Deoxyribonucleic acid methylation in mycobacteria.