Electromagnetic fields and acute lymphocytic leukemia in children living in the Metropolitan Area of Sao Paulo / Campos eletromagnéticos e leucemia linfocítica aguda em crianças residentes na região metropolitana de São Paulo

AUTOR(ES)

Daniele Maria Pelissari

DATA DE PUBLICAÇÃO

2009

RESUMO

Introduction-The Acute Lymphocytic Leukemia (ALL) is the most common cancers in children. Some epidemiological studies have identified increased risk of ALL in children exposed to magnetic fields generated by high voltage power lines, however, this association was not confirmed by other studies. Purpose- Check the association between exposure to magnetic fields and the incidence of ALL in children residing in the Metropolitan Region of São Paulo, considering the distance from childrens home and transmission lines (88, 138, 230, 345 and 440 kV). Methods- A population-based case-control study. The cases were selected in five hospitals in the city of Sao Paulo, which account for the care of children with ALL. Four population controls were selected for each case, matched by sex, age and city of birth. Cases and controls were interviewed using a similar questionnaire to obtain information on the interest variables and potential confounding variables. The homes were evaluated by distances of the nearest transmission lines using the Global Positioning System (GPS). To examine the association between magnetic fields and ALL was used conditional logistic regression, including the control of potential confounding variables. We calculated the odds ratios (OR) and their 95per cent confidence interval (95 per cent CI). Results-The association between the distance of transmission lines and ALL was adjusted by education of the person interviewed, and the OR was 2.91 (95 per cent CI 0.92-9.22). Conclusion- Children living at less than 160 m of power transmission lines in RMSP have higher risk, though not statistically significant, when compared with those living in more than 160 m.

ASSUNTO(S)

região metropolitana de são paulo leucemia linfocítica aguda na infância linhas de transmissão estudo caso-controle magnetic fields campos magnéticos childhood acute lymphocytic leukemia transmission lines metropolitan area of sao paulo case-control study

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