Electrochemiluminescence Detection of Silver Ion Based on Trigeminal Structure of DNA
AUTOR(ES)
Li, Zhejian
FONTE
J. Braz. Chem. Soc.
DATA DE PUBLICAÇÃO
23/05/2019
RESUMO
A novel electrochemiluminescence (ECL) biosensor for highly sensitive and selective detection of Ag+ is developed based on the sensitive “turn-on” structure-switching trigeminal structure of deoxyribonucleic acid (DNA-TS). DNA-TS consists of three oligonucleotides hybridized to form three double-stranded DNA like Y-shaped DNA structure. The formation of DNA-TS makes the ECL sign Ru(bpy)2(mcbpy-O-Su-ester)(PF6)2 of reporter probe approach to the electrode surface and thus increase the ECL signal intensity. The “signal-on” ECL biosensor could detect Ag+ concentration in the range from 1.0 × 10-11 to 3.2 × 10-9 mol L-1, and the limit of detection is 3.0 × 10-12 mol L-1. The strategy is sensitive and rapid. This approach could be extended to the design of sensors for other desired heavy metal ions as well. Such ECL sensors are promising for sensitive detection of other heavy metal ions.
Documentos Relacionados
- Cytomegalovirus glycoprotein B-specific antibody analysis using electrochemiluminescence detection-based techniques.
- Detection of human immunodeficiency virus type 1 proviral DNA by PCR using an electrochemiluminescence-tagged probe.
- AN ELECTROCHEMILUMINESCENCE SANDWICH BIOSENSOR FOR THE DETECTION OF LIPOPOLYSACCHARIDE
- An Electrochemiluminescence Biosensor for the Determination of Mercury Ion via Dual-Amplification Strategy
- Effect of Silver Ion, Carbon Dioxide, and Oxygen on Ethylene Action and Metabolism 1
