Efficacy of combined treatment with oral and topical acyclovir in first episode genital herpes.

AUTOR(ES)

Kinghorn, G R

RESUMO

Fifty patients presenting with first episode genital herpes were randomly allocated to seven day treatment with either oral acyclovir plus 5% acyclovir cream or oral acyclovir plus matching placebo cream. Combined treatment with oral and topical acyclovir was associated with a shorter duration of itching in women alone (p = 0.04) but gave no clinical relief of other symptoms, the time to healing of lesions, or the subsequent recurrence rate. Concomitant topical treatment with 5% acyclovir cream confers no advantages on patients who receive oral acyclovir.

Documentos Relacionados

• Efficacy of oral treatment with acyclovir and co-trimoxazole in first episode genital herpes.
• Topical acyclovir in the treatment of initial genital herpes.
• A prospective study of the psychological impact on patients with a first episode of genital herpes.
• Topical polyriboinosinic-polyribocytidylic acid complex in the treatment of recurrent genital herpes.
• The effect of suppressive oral acyclovir on the psychological morbidity associated with recurrent genital herpes.