Efficacy of ciprofloxacin against Leptospira interrogans serogroup icterohaemorrhagiae.
AUTOR(ES)
Shalit, I
RESUMO
Ciprofloxacin activity against Leptospira interrogans serogroup icterohaemorrhagiae was studied in vitro and in an animal model. The MBC of ciprofloxacin was 0.6 microgram/ml. Three of three Syrian hamsters died 8 to 9 days after intraperitoneal challenge with 10(6) leptospires. In contrast, five of six animals given ciprofloxacin 3 or 5 days after challenge survived.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=172537Documentos Relacionados
- Scattering of the rRNA genes on the physical map of the circular chromosome of Leptospira interrogans serovar icterohaemorrhagiae.
- Effect of mycolic acid and its derivatives on the growth of Leptospira icterohaemorrhagiae.
- STUDIES ON LEPTOSPIRA ICTEROHAEMORRHAGIAE. II. A CRITICAL STUDY OF THE EFFECT OF PENICILLIN ON LEPTOSPIRA ICTEROHAEMORRHAGIAE IN VITRO AND IN LEPTOSPIROSIS IN GUINEA PIGS
- Restriction endonuclease DNA analysis of Leptospira interrogans serovars icterohaemorrhagiae and hebdomadis.
- Tissue apoptosis in mice infected with
Leptospira interrogans serovar Icterohaemorrhagiae
