Effects of fatty acids on lysis of Streptococcus faecalis.
AUTOR(ES)
Carson, D D
RESUMO
Palmitic, stearic, oleic, and linoleic acids at concentrations of 200 nmol/ml all inhibited autolysin activity 80% or more in whole cells or cell-free extracts. This concentration of the saturated fatty acids palmitic acid and stearic acid had little or no effect on the growth of whole cells or protoplasts. However, the unsaturated fatty acids oleic acid and linoleic acid induced lysis in both situations. This lytic effect is apparently not related to any uncoupling activity or inhibition of energy catabolism by unsaturated fatty acids. It is concluded that unsaturated fatty acids induce cell and protoplast lysis by acting as more potent membrane destabilizers than saturated fatty acids.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=293793Documentos Relacionados
- Effect of lipoteichoic acid and lipids on lysis of intact cells of Streptococcus faecalis.
- Effects of temperature on the autolytic enzyme system of Streptococcus faecalis.
- Effects of cerulenin on antibiotic-induced lysis of streptococcus faecalis (S. faecium).
- Autolytic defective mutant of Streptococcus faecalis.
- Recombination-deficient mutant of Streptococcus faecalis.
