Effects of 16S rRNA Gene Mutations on Tetracycline Resistance in Helicobacter pylori
AUTOR(ES)
Gerrits, Monique M.
FONTE
American Society for Microbiology
RESUMO
The triple-base-pair 16S rDNA mutation AGA926-928→TTC mediates high-level tetracycline resistance in Helicobacter pylori. In contrast, single- and double-base-pair mutations mediated only low-level tetracycline resistance and decreased growth rates in the presence of tetracycline, explaining the preference for the TTC mutation in tetracycline-resistant H. pylori isolates.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=182601Documentos Relacionados
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