EFFECT OF TRANEXAMIC ACID ON BLEEDING CONTROL IN TOTAL KNEE ARTHROPLASTY
AUTOR(ES)
SADIGURSKY, DAVID, ANDION, DANIEL, BOUREAU, PÉRICLES, FERREIRA, MARIA CORDULINA, CARNEIRO, ROGÉRIO JAMIL FERNANDES, COLAVOLPE, PAULO OLIVEIRA
FONTE
Acta ortop. bras.
DATA DE PUBLICAÇÃO
2016-06
RESUMO
ABSTRACT Objectives: To analyze the effectiveness of intravenous (IV) tranexamic acid (TA) in reducing blood loss in total knee arthroplasty (TKA). Method: The population sample was composed of patients with a diagnosis of primary knee osteoarthritis. The patients undergoing TKA were divided in two groups. Group A: comprised patients who used IV TA and B group, formed by patients who did not use TA in the intra or post-operative period. For descriptive analysis, quantitative variables were represented by mean and standard deviations when their distribution was normal and interquartile ranges and medians for non-normal variables. Results: The mean age of patients was 68 years old, most of them were female and with involvement of the left knee. Postoperatively patients who had used IV TA showed less bleeding rate and less hemoglobin rate reduction. Conclusion: The use of IV TA in TKA reduces blood loss in peri- and postoperative periods. Regarding total blood loss reduction, hemoglobin rate and need for blood transfusions, IV TA should be used routinely during TKA since it has been shown to be safe with no increase in side effects as thromboembolic events. Level of Evidence III. Retrospective Comparative Study.
Documentos Relacionados
- Comparison of Floseal® and Tranexamic Acid for Bleeding Control after Total Knee Arthroplasty: a Prospective Randomized Study
- Effect of patellar resurfacing surgery on bleeding in total knee arthroplasty
- PLATELET-RICH PLASMA (PRP) AND TRANEXAMIC ACID (TXA) APPLIED IN TOTAL KNEE ARTHROPLASTY
- The Role of Tranexamic Acid in the Prevention and Management of Blood Loss in Total Joint Arthroplasty
- Tranexamic acid in total shoulder arthroplasty under regional anesthesia: a randomized, single blinded, controlled trial