Effect of Clostridium difficile toxin A on CD11/CD18 expression in vitro.
AUTOR(ES)
Warny, M
RESUMO
Clostridium difficile toxin A is chemotactic for neutrophils and induces their emigration into the colonic mucosae of rodents. We found that toxin A did not upregulate neutrophil beta 2 integrins on isolated human neutrophils. These data support the hypothesis that in C. difficile colitis, these adhesion molecules are upregulated by endogenous mediators.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=170416Documentos Relacionados
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