Effect of Carbon Dioxide and pH on Susceptibility of Bacteroides fragilis Group to Erythromycin

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RESUMO

We examined the effects of pH and incubation in a CO2-containing atmosphere on the activity of erythromycin against 81 strains of the Bacteroides fragilis group. A striking reduction in erythromycin activity was noted when the pH decreased below 7.0 and when the organisms were incubated with CO2.

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