Efeito de quatro anitibioticos sobre larvas de Chrysomya putoria (Wiedewann) (Diptera: Calliphoridae) utilizadas em bioterapia

AUTOR(ES)
DATA DE PUBLICAÇÃO

2005

RESUMO

Biotherapy or maggot debridement therapy is the use of live blow-fly larvae for treating non-healing wounds. This kind of treatment was discovered accidentally in battle field conditions, was commonly practiced during 1930?s and 1940?s and presently has been used in several countries. Larvae applied in the wound promote healing by several mechanisms such as liquefing necrotic tissue, removing bacteria, and by secretion of substances that help healing and stimulate the growth of granulation tissue. Maggot therapy use is relatively simple, a non expensive therapy that promote good results where sometimes conventional therapies are not effective. In this work the species Chrysomya putoria (Wiedemann) (Diptera: Calliphoridae) was selected and raised under laboratory conditions for the future use of maggot therapy in animals. Since the animal skin wounds are usually infected, in this work the effects of Ampicilin, Amoxicilin, Cefalexin and Cefalotin were tested on growth and development of C. putoria larvae to compare with one or more of the tested drugs that will be utilized in association with larval debridement therapy in animals. Antibiotics were used in different concentrations and added to the medium used as growth substract for C. putoria. The growth and developmental rates as well the number of surviving pupae were recorded. Three replicates and one control were done for each antibiotic type and concentration tested. Amoxicilin was the drug with the least detrimental effect upon the larvae and, therefore, was considered the safest to be used in association with maggot therapy

ASSUNTO(S)

terapia larval chrysomya putoria desenvolvimento larval feridas e lesões - tratamento

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