Efeito da utilização de plasma rico em plaquetas na osteointegração dos enxertos ósseos homólogos criopreservados: estudo histomorfométrico em coelhos / Effects of platelet rich plasma in osteointegration of cryopreserved homologous bone grafts: histomorphometric study in rabbits

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

Bone loss, in some segments of the muscle-skeleton system, are of great concern in the fields of Orthopedics and Traumatology. There are several options of treatment by means of bone grafts and growth factors. In this study we evaluate the effect of platelet rich plasma (PRP) in the initial phase of osteointegration of cryopreserved (- 80 °C) homologous bone grafts, in blocks, implanted in the femoral condyles of rabbits. We operated 19 animals (38 femurs). Both techniques were applied in the same animal in alternate sides. In one side we applied isolated allograft (side 1) and on the contralateral side we added PRP to the allograft (side 2). After 15 days, the animals were sacrificed and the femoral condyles, with the receptor area, were analyzed histomorphometrically (semi-automatic method). We found no effect of the PRP in the receptor. The comparison between the histomorphometric parameters of structural, formation and bone resorption showed no significant differences.

ASSUNTO(S)

plasma rico em plaquetas coelhos tissue banks criopreservação/métodos platelet-rich plasma banco de tecidos transplante homólogo skeletal muscle/transplantation cryopreservation/methods. homologous transplantation músculo esquelético/transplante

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