Efeito da obesidade sobre a forÃa dos mÃsculos respiratÃrios e centro respiratÃrio

AUTOR(ES)
DATA DE PUBLICAÇÃO

2008

RESUMO

Background: The obesity affects many organs and systems of human body, prejudicing vital functions by immunologic, circulatory, hormonal and respiratory functions. On the respiratory system, obesity results in a reduction of lung volumes and flows. Also take a reduction on the respiratory compliance and an increment on the total respiratory resistance. Methods: The purpose of this study, is evaluate how the obesity levels could affect the pulmonary volumes (CV, CVF and Vt), flows (VEF1, PEF and FEF25%), resistive proprieties (R5Hz), respiratory muscle strength (Pimax and Pemax) and respiratory drive (P0.1). We analyze 65 individuals, divided into 5 groups according with their BMI: overweight / control (C), obese (OB), morbid obese I (OM I), morbid obese II (MO II) and morbid obese (MO III). We use ANOVA or Kruskal Wallis test to analyze all variables, Tukey or Dunnâs test to compare means group by group and linear regression to analyze association between variables and BMI. Results: The pulmonary volumes and flows have significant reduction with increment of BMI in both analyses (p <0.05, ANOVA and Kurskal Wallis), also had a strong correlation with the increase on BMI. The increment on BMI produce a higher value on the total respiratory resistance (R5Hz) (p <0.05, Kurskal Wallis) and shows again a strong correlation with a higher BMI. In spite of this, the respiratory muscle strength and respiratory drive do not show any reduction and any correlation with BMI. Conclusion: We conclude that an increase on BMI makes a reduction in pulmonary functions altered the resistive proprieties of respiratory system, but do not affect the muscle strength and respiratory drive

ASSUNTO(S)

Ãndice de massa corpÃrea (imc) obesity resistÃncia do sistema respiratÃrio p0.1 ciencias biologicas pemax pimax pemax funÃÃo pulmonar lung function body mass index (bmi) obesidade pimax respiratory system resistance p0.1

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