Efeito da concentração de sacarose no biofilme dental formado in situ no desenvolvimento de carie

AUTOR(ES)
DATA DE PUBLICAÇÃO

2004

RESUMO

Considering that the relationship between sugar concentration and caries is not clearly established, the objective of the present study was to evaluate the acidogenicity and the composition of biofilm formed in situ in the presence of different sucrose concentrations and its relation with the initiation and the progression of dental caries. Thus, a blind and cross-over study was conducted, with 3 experimental phases of 14 days each. Adult volunteers wore intra-oral palatal appliances containing 4 blocks of human dental enamel, which were submitted 8 x/day treatments: deionized distilled water, 1, 5, 10, 20 and 40% sucrose solution. In each experimental phase, 2 treatments were evaluated, considering that each pair of dental blocks in a side of the appliance received a different treatment, randomly defined: deionized distilled water and 1% sucrose; 10 and 20% sucrose; 5 and 40% sucrose. The volunteers used non-fluoridated dentifrice in the lead-in and washout periods and during the experimental phases. At the end of each experimental phase, the acidogenicity (baseline pH and 5 minutes after treatment), inorganic composition and insoluble polyssacharide of dental biofilm formed on the enamel blocks were analyzed; percentage of surface microhardness change (%SMC) and area of mineral loss (DZ) were determined on enamel. The results suggest that the threshold of sucrose concentration for the formation a cariogenic biofilm was 5%, providing a cariogenic potential as outstanding as that observed in 10 and 20%. In addition, carbohydrate concentration at 40% was able to enhance the cariogenic properties of dental biofilm, increasing enamel demineralization.

ASSUNTO(S)

polissacarideos microeletrodos

ACESSO AO ARTIGO

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