Dominant character of the molecular marker of a Biomphalaria tenagophila strain (Mollusca: Planorbidae) resistant to Schistosoma mansoni

AUTOR(ES)

Rosa, Florence Mara, Caldeira, Roberta Lima, Carvalho, Omar dos Santos, Godard, Ana Lúcia Brunialti, Coelho, Paulo Marcos Zech

FONTE

Memórias do Instituto Oswaldo Cruz

DATA DE PUBLICAÇÃO

2004-02

RESUMO

Biomphalaria tenagophila population from Taim (state of Rio Grande do Sul, Brazil) is totally resistant toSchistosoma mansoni, and presents a molecular marker of 350 bp by polymerase chain reaction and restriction fragment length polymorphism of the entire rDNA internal transcriber spacer. The scope of this work was to determine the heritage pattern of this marker. A series of cross-breedings between B. tenagophila from Taim (resistant) and B. tenagophila from Joinville, state of Santa Catarina (susceptible) was carried out, and their descendants F1 and F2 were submitted to this technique. It was possible to demonstrate that the specific fragment from Taim is endowed with dominant character, since the obtained segregation was typically mendelian.

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