Does perfluorocarbon deoxygenate during partial liquid ventilation?

AUTOR(ES)

Hirschl, Ronald B

FONTE

BioMed Central

RESUMO

Perfluorocarbons accumulate in the dependent regions of the lungs, which may result in regional hypoxia if ventilation with oxygen is insufficient to oxygenate the dependent perfluorocarbon-filled alveoli. In this issue of Critical Care, Max et al present data that demonstrate a decrease in arterial oxygen tension (PaO2) at 30 min compared to that observed at 5min after administration of FC 3280. These data suggest failure of on-going attributed to the oxygen ventilation/oxygenation to support the initial increase in PaO2dissolved in the administered perfluorocarbon. Studies such as this one demonstrate that development of the optimal partial liquid ventilation (PLV) technique is ongoing.

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