Diphenylhydantoin Inhibition of Sodium Conductance in Squid Giant Axon
AUTOR(ES)
Lipicky, Raymond J.
RESUMO
Diphenylhydantoin, in concentration of 5-50 μM, decreases the early, transient (sodium) currents of voltage-clamped squid giant axons. These effects are dose-dependent and largely reversible. It appears that diphenylhydantoin reduces the number of open, early, transient (sodium) channels.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=426796Documentos Relacionados
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