Dihydroethanoanthracene Derivatives as In Vitro Malarial Chloroquine Resistance Reversal Agents
AUTOR(ES)
Millet, Julie
FONTE
American Society for Microbiology
RESUMO
The ability of four 9,10-dihydroethanoanthracene derivatives (BG920, BG932, BG958, and BG996), as well as verapamil and promethazine, to reverse chloroquine resistance was assessed against 24 chloroquine-resistant and 10 chloroquine-susceptible strains of Plasmodium falciparum from different countries. The 9,10-dihydroethanoanthracene derivatives clearly increase chloroquine susceptibility only in chloroquine-resistant isolates.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=434228Documentos Relacionados
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