Diagnosis and treatment of systemic mastocytosis in Brazil: Recommendations of a multidisciplinary expert panel

AUTOR(ES)

Velloso, Elvira D. Rodrigues Pereira; Padulla, Geórgia A.; Cerqueira, Ana Maria Mósca de; Sousa, Adriana Martins de; Sandes, Alex Freire; Traina, Fabiola; Seguro, Fernanda Salles; Nogueira, Frederico Lisboa; Pereira, Grazielly de Fátima; Boechat, José Laerte; Pagnano, Katia Borgia Barbosa; Marchi, Luan Lima; Ensina, Luis Felipe; Giavina-Bianchi, Mara; Aun, Marcelo Vivolo; Agondi, Rosana Câmara; Santos, Fabio Pires de Souza; Giavina-Bianchi, Pedro

FONTE

Hematology, Transfusion and Cell Therapy

DATA DE PUBLICAÇÃO

2022

RESUMO

ABSTRACT Introduction: Systemic Mastocytosis comprises a group of neoplastic diseases characterized by clonal expansion and infiltration of mast cells into several organs. The diagnosis and treatment of this disease may be challenging for non-specialists. Objective: Make suggestions or recommendations in Systemic Mastocytosis based in a panel of Brazilian specialists. Method and results: An online expert panel with 18 multidisciplinary specialists was convened to propose recommendations on the diagnosis and treatment of Systemic Mastocytosis in Brazil. Recommendations were based on discussions of topics and multiple-choice questions and were graded using the Oxford Centre for Evidence-Based Medicine 2011 Levels of Evidence Chart. Conclusion: Twenty-two recommendations or suggestions were proposed based on a literature review and graded according to the findings.

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