Development and Validation of a High-Performance Liquid Chromatography Assay for Voriconazole

AUTOR(ES)
FONTE

American Society for Microbiology

RESUMO

An analytical method for the determination of voriconazole (UK-109,496; Pfizer) in plasma was developed and validated. The method utilizes solid-phase extraction technology and high-performance liquid chromatography. The lower limit of quantitation is 0.2 μg/ml, and the range of linearity tested was 0.2 to 10 μg/ml.

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