Detection of rpoB Mutations in Mycobacterium tuberculosis by Biprobe Analysis
AUTOR(ES)
Edwards, K. J.
FONTE
American Society for Microbiology
RESUMO
A biprobe assay utilizing LightCycler technology was developed to detect rifampin resistance-associated gene mutations in the Mycobacterium tuberculosis rpoB gene. Three biprobes detected all mutations present in the 46 rifampin-resistant isolates. Wild-type sequences were correctly identified in each case. The method was reproducible, accurate, and easy to use.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=88343Documentos Relacionados
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