Description of a new experimental model skin flap for studying skin viability in rats

AUTOR(ES)

Camargo, Cristina Pires, Margarido, Nelson Fontana, Guandelini, Eduardo, Vieira, Guilherme Alexandre Barrucci, Jacomo, Alfredo Luiz, Gemperli, Rolf

FONTE

Acta Cir. Bras.

DATA DE PUBLICAÇÃO

2014-03

RESUMO

PURPOSE: To describe a new experimental flap for studying skin viability in rats.METHODS: Twenty male Wistar rats weighing between 250-300g were divided into two groups: group A - McFarlane technique, a 4 x 10cm flap was used (McFarlane); and in group B modified McFarlane technique, a 3 x 10cm flap was used. Seven days later, the animals were sacrificed and the area of necrosis was evaluated in both groups.RESULTS: Group A presented necrosis in 3% of the total area of the flap (CI: 0.01-0.05), Group B presented necrosis in 37% of the total area of the flap (CI: 0.29-0.46), (p<0.001).CONCLUSION: The modified McFarlane flap presented a larger area of necrosis and could be an adequate experimental model of skin flap viability.

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