Decreased Adrenal Responsiveness to Angiotensin II: A Defect Present in Spontaneously Hypertensive Rats: A POSSIBLE MODEL OF HUMAN ESSENTIAL HYPERTENSION

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RESUMO

30% of patients with essential hypertension have a decreased adrenal response to angiotensin II (A II) on a low but not a high sodium intake. They also have a compensatory increase in the activity of the renin-angiotensin system best documented in a sodium-restricted state.

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