Dapsone syndrome with acute renal failure during leprosy treatment: case report

AUTOR(ES)

Alves-Rodrigues, Edson Nogueira, Ribeiro, Luciano Correa, Silva, Margareth Dióz, Takiuchi, Arley, Fontes, Cor Jesus Fernandes

FONTE

Brazilian Journal of Infectious Diseases

DATA DE PUBLICAÇÃO

2005-02

RESUMO

Dapsone syndrome is a rare hypersensitivity reaction to dapsone and is characterized by high fever, papular or exfoliative dermatitis, progressing to liver toxicity and generalized lymphadenopathy, resembling a mononucleosis infection. We report a patient who developed acute renal failure, as well as other complications characteristic of dapsone syndrome, during leprosy treatment. Renal involvement had not been previously described as a dapsone syndrome feature.

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