Cytoplasmic particles in hepatocytes of patients with Australia antigen-positive liver disease

AUTOR(ES)
RESUMO

An electron microscope study was made of liver biopsy material obtained during life or shortly after death from 11 patients. In three of them, where serum was positive for Australia antigen (two had serum hepatitis and one active chronic hepatitis) the hepatocytes contained characteristic particles within membrane-bound cytoplasmic vesicles. The appearance of these particles was very similar to that of the Australia antigen particles found in the serum.

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