Crystallization of the receptor-binding domain of parathyroid hormone-related protein in complex with a neutralizing monoclonal antibody Fab fragment
AUTOR(ES)
McKinstry, William J.
FONTE
International Union of Crystallography
RESUMO
A Fab fragment of a monoclonal anti-parathyroid hormone-related protein antibody was prepared and its complex with parathyroid hormone-related protein was crystallized. X-ray diffraction data were collected to 2.0 Å resolution.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=2664753Documentos Relacionados
- Direct mapping of an agonist-binding domain within the parathyroid hormone/parathyroid hormone-related protein receptor by photoaffinity crosslinking
- Structure of the receptor-binding domain of human thrombopoietin determined by complexation with a neutralizing antibody fragment
- Parathyroid hormone-related peptide.
- Molecular cloning of the gene encoding the mouse parathyroid hormone/parathyroid hormone-related peptide receptor.
- Activated parathyroid hormone/parathyroid hormone–related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone
