Convenient Biological Assay for Polyethylene Glycol-Interferons in Patients with Hepatitis C

AUTOR(ES)

Boulestin, Anne

FONTE

American Society for Microbiology

RESUMO

The vesicular stomatitis virus cytopathic effect reduction assay is suitable to quantify polyethylene glycol-alpha interferon 2a (PEG-IFN-α2a) and PEG-IFN-α2b. Human serum and ribavirin did not interfere with the assay. This bioassay was successfully used for assaying PEG-IFN-α2a and PEG-IFN-α2b in serum samples from patients undergoing combination therapy.

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