Controlled release levodopa treatment of motor fluctuations in Parkinson's disease.
AUTOR(ES)
Juncos, J L
RESUMO
A controlled release preparation of levodopa-carbidopa, CR III, given every 4 hours to 17 Parkinsonian patients for up to 10 months reduced plasma drug variations and improved motor response fluctuations compared with standard levodopa-carbidopa given every 2 hours. The results support the value of pharmaceutical approaches to the stabilisation of circulating levodopa levels in the treatment of Parkinson's disease.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=1031491Documentos Relacionados
- A comparison of the effects of controlled-release levodopa (Madopar CR) with conventional levodopa in late Parkinson's disease.
- Motor response to apomorphine and levodopa in asymmetric Parkinson's disease.
- Motor response to apomorphine and levodopa in asymmetric Parkinson's disease.
- Levodopa peripheral pharmacokinetics and duration of motor response in Parkinson's disease.
- Comparison of motor response to apomorphine and levodopa in Parkinson's disease.