Control Mechanisms Operative in a Natural Microbial Population Selected for its Ability to Degrade L-Lysine. I. Effect of Glucose in Batch Systems
AUTOR(ES)
Grady, C. P. L.
RESUMO
A natural microbial population was selected in a medium containing L-lysine as the sole carbon source and ammonia as a nitrogen source. Cells were harvested from a batch-operated fermentor containing lysine and were grown through one transfer on lysine, glucose, or a mixture of lysine and glucose. By comparing the substrate removal rates and enzymatic capabilities of the cells, it was determined that the inducible enzyme system responsible for lysine degradation was subject to catabolic repression. Inhibition of the activity of preformed enzyme(s) played only a minor role. Preinduction by lysine offered only a small degree of protection against repression. The removal of ammonia nitrogen from the system did not overcome the effect of glucose.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=378088Documentos Relacionados
- Control Mechanisms Operative in a Natural Microbial Population Selected for Its Ability to Degrade L-Lysine. II. Effects of Fructose and Ribose in Batch Systems
- Control Mechanisms Operative in a Natural Microbial Population Selected for Its Ability to Degrade L-Lysine. III. Effects of Carbohydrates in Continuous-Flow Systems Under Shock Load Conditions
- Unbalance of L-lysine flux in Corynebacterium glutamicum and its use for the isolation of excretion-defective mutants.
- Sugar Substrates for l-Lysine Fermentation by Ustilago maydis
- Effect of polymers of L-lysine on the cytotoxic action of diphtheria toxin.