Contiguous stereogenic quaternary carbons: A daunting challenge in natural products synthesis

AUTOR(ES)

Peterson, Emily A.

FONTE

National Academy of Sciences

RESUMO

One element of structure that invariably increases the difficulty of a chemical synthesis is the presence in the target molecule of contiguous all-carbon quaternary stereocenters. This Perspective will examine the most useful transformations and strategies devised recently for directly assembling this structural unit.

Documentos Relacionados

• CHLORDECONE ADSORPTION ON FUNCTIONALIZED ACTIVATED CARBONS: COMPUTATIONAL CHEMISTRY AS A TOOL FOR UNDERSTANDING THE ADSORPTION PROCESS
• Highlights in the solid-phase organic synthesis of natural products and analogues
• Terpene Esters from Natural Products: Synthesis and Evaluation of Cytotoxic Activity
• Natural regeneration in a quaternary coastal plain in southern Brazilian Atlantic Rain forest
• Computer-Guided Total Synthesis of Natural Products. Recent Examples and Future Perspectives