Constituintes químicos de Galianthe brasiliensis (RUBIACEAE)
AUTOR(ES)
Moura, Vagner Marques de, Santos, Daniela Pereira dos, Santin, Silvana Maria de Oliveira, Carvalho, João Ernesto de, Foglio, Mary Ann
FONTE
Química Nova
DATA DE PUBLICAÇÃO
2006-06
RESUMO
This paper describes the chemical constituents isolated from aerial parts of the plant Galianthe brasiliensis. From a methanol extract, the iridoid glycosides asperuloside, deacetylasperuloside, mixture of Z- and E-6-O-p-coumaroylscandoside methyl ester, the triterpene ursolic acid and the steroids stigmasterol, campesterol, beta-sitosterol and 3-O-beta-glycopiranosyl sitosterol were isolated. The structures of the natural products were identified on the basis of spectral data, including 2D NMR experiments. The antiproliferative properties of the crude methanolic extract were investigated against a series of nine human cancer cell lines.
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