Complete plasmid sequence carrying type IV-like and type VII secretion systems from an atypical mycobacteria strain

AUTOR(ES)

Morgado, Sergio Mascarenhas, Marín, Michel Abanto, Freitas, Fernanda S, Fonseca, Erica Lourenço, Vicente, Ana Carolina Paulo

FONTE

Mem. Inst. Oswaldo Cruz

DATA DE PUBLICAÇÃO

2017-07

RESUMO

The genus Mycobacterium is highly diverse and ubiquitous in nature, comprehending fast- and slow-growing species with distinct impact in public health. The plasmid-mediated horizontal gene transfer represents one of the major events in bacteria evolution. Here, we report the complete sequence of a 160,489 bp circular plasmid (pCBMA213_2) from an atypical and fast-growing environmental mycobacteria. This is a unique plasmid, in comparison with the characterised mycobacteria plasmids, harboring a type IV-like and ESX-P2 type VII secretion systems. pCBMA213_2 can be further explored for evolutionary and conjugation studies as well as a tool to manipulate DNA within this bacteria genus.

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