Complete genetic characterization of a Brazilian dengue virus type 3 strain isolated from a fatal outcome

AUTOR(ES)
FONTE

Memórias do Instituto Oswaldo Cruz

DATA DE PUBLICAÇÃO

2006-05

RESUMO

We have determined the complete nucleotide and the deduced amino acid sequences of Brazilian dengue virus type 3 (DENV-3) from a dengue case with fatal outcome, which occurred during an epidemic in the state of Rio de Janeiro, Brazil, in 2002. This constitutes the first complete genetic characterization of a Brazilian DENV-3 strain since its introduction into the country in 2001. DENV-3 was responsible for the most severe dengue epidemic in the state, based on the highest number of reported cases and on the severity of clinical manifestations and deaths reported.

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