Comparison of thyroid stimulating hormone and triiodothyronine response to thyrotrophin releasing hormone in the assessment of thyroid status.
AUTOR(ES)
Squire, C R
RESUMO
The response to an intravenous dose of 200 microng of thyrotrophin releasing hormone (TRH) has been studied by estimating, by radioimmunoassay, baseline levels followed by further estimations of thyroid stimulating hormone (TSH) 20 minutes after the injection and triiodothyronine (T3) three hours after the injection in 112 patients referred for routine thyroid assessment. Comparison of diagnostic accuracy of the response to TRH gave similar results with both procedures but slightly better overall accuracy for the response measured by TSH assay. However, estimation of baseline T3 is a valuable test for hyperthyroidism, in contrast to baseline TSH, and combined with the estimation of T3 three hours after TRH injection provides an accurate additional test in borderline cases.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=476503Documentos Relacionados
- Pressor effects of thyrotrophin releasing hormone during thyroid function testing.
- Thyroid Hormone Inhibition of the Prolactin Response to Thyrotropin-Releasing Hormone
- Normal pituitary hormone response to thyrotrophin and gonadotrophin releasing hormones in subjects exposed to elemental mercury vapour.
- Thyroid antoantibodies and the response to thyrotropin releasing hormone in patients with subclinical hypothyroidism.
- The Physiological Role of Thyrotropin-Releasing Hormone in the Regulation of Thyroid-Stimulating Hormone and Prolactin Secretion in the Rat