Comparative study between biochemical and histological methods and image analysis in liver iron overload.
AUTOR(ES)
Deugnier, Y
RESUMO
Iron overload has been measured in 100 hepatic biopsies by three different methods: (i) biochemical assay of the liver iron concentration (LIC), (ii) histological grading (HISTO) and (iii) automated image analysis with a Leitz Texture Analysis System by estimating two parameters, (a) the total iron area (TIA) and (b) the first grey level step (FGLS) at which the iron is detected. Image analysis appears as a specific, sensitive, quick, reproducible and valid method.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=497446Documentos Relacionados
- Synovial biopsy in haemochromatosis arthropathy. Histological findings and iron deposition in relation to total body iron overload.
- Malondialdehyde and 4-hydroxynonenal protein adducts in plasma and liver of rats with iron overload.
- Arthropathy of haemochromatosis. Clinical and radiological analysis of 63 patients with iron overload.
- Hepatic lipid peroxidation in vivo in rats with chronic iron overload.
- Lysozyme in chronic liver disease: a biochemical and histological study.