Comparative Phytochemistry between specimens of the Mikania cordifolia (L. f.) Willd / Estudo fitoquímico comparativo entre espécies de mikania cordifolia (L. F.) WILLD

AUTOR(ES)
DATA DE PUBLICAÇÃO

2007

RESUMO

In the present work, specimens of Mikania cordifolia collected at Ribeirão Preto, São Carlos, Campos do Jordão and Monte Verde were analyzed comparatively for triterpenoids, sesquiterpene lactones and flavonoids by chromatographic methods (GC and HPLC). All M. cordifolia specimens analyzed showed the triterpenoids -Amyrin, - Amyrin, Lupeol, Lupenone, Taraxasterol, Pseudotaraxasterol, -Amyrin Acetate, - Amyrin Acetate, Lupeol Acetate, Taraxasterol Acetate, Campesterol, Stigmasterol e -Sitosterol, the sesquiterpene lactones 14-hydroxy-15[2 -hydroxymethylacryloyloxygermacra- 1(10)E,4Z-11(13)-trien-12,8 -olide, 14-hydroxy-15[2 -hydroxy,2 - methylpropanoyloxy]-germacra-1(10)E,4Z-11(13)-trien-12,8 -olide e 14-hydroxy- 15[2 ,3 -epoxy,2 -methylpropanoyloxy]-germacra-1(10)E,4Z-11(13)-trien-12,8 -olide, the flavonoids Quercetin-3-O- -galactoside and Rhamnazyn and the compound 3,4- dihydroxy-benzoic acid. Only specimens collected at Ribeirão Preto and São Carlos showed Friedelin. The aqueous extract of M. cordifolia was evaluated for antiofidic activity and was found effective in reducing mice paw edema induced by venom of Bothrops moojeni

ASSUNTO(S)

phytochemical study mikania eupatorieae mikania cordifolia (l. f.) willd asteraceae asteraceae

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