Comparative evaluation of commercial fluorescent treponemal antibody-absorbed test kits.
AUTOR(ES)
Beebe, J L
RESUMO
We describe a comparative evaluation of commercial fluorescent treponemal antibody-absorbed test kits, using 150 selected patient sera. The ability of the test kits to detect reactive sera varied from 82.5 to 95%; that for nonreactive sera varied from 80.9 to 96.4%. Reproducibility of reactive and nonreactive results, measured by between-assay and within-assay studies, averaged 42%. The results showed substantial variation in performance characteristics among the kits, with important clinical implications for the diagnosis of syphilis. We recommend the development of an immunological standard for use in the manufacture of fluorescent treponemal antibody-absorbed test kits, with the goal of obtaining uniform performance characteristics among commercial test kits.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=271186Documentos Relacionados
- Percoll-purified Treponema pallidum, an improved fluorescent treponemal antibody-absorbed antigen.
- Comparative evaluation of commercial rubella virus antibody kits.
- False-positive reactions in the rapid plasma reagin-card, fluorescent treponemal antibody-absorbed, and hemagglutination treponemal syphilis serology tests.
- Neonatal congenital syphilis. Diagnosis by the absorbed fluorescent treponemal antibody (IgM) test.
- Fluorescent Treponemal Antibody Absorption Double-Staining Test Evaluation