Colon cancer and swimming exercise: effect on wistar rat testes

AUTOR(ES)

Freitas, Karine Moura de, Natali, Antônio José, Lunz, Wellington, Costa, Kyvia Lugate Cardoso, Leite, Rodrigo Paula, Dolder, Heidi, Matta, Sérgio Luis Pinto da

FONTE

Braz. arch. biol. technol.

DATA DE PUBLICAÇÃO

2013-08

RESUMO

This study was undertaken to determine whether colon cancer (CC) and chronic swimming exercise alter rat testis. Eleven weeks old rats were distributed into control group (n=6) and the groups that were induced to develop CC by dimethylhydrazine injections (nEG, EG0, EG2 and EG4; n=10 each group). In the group nEG, the rats did not swim, whereas groups EG0, EG2 and EG4, underwent a swimming program with distinct loads (0, 2 and 4% of body mass, respectively) for 35 weeks. The morphometry, stereology and cell counts showed damage caused by the CC on the germ epithelium. These results were noteworthy since this was the first report to associate the CC with testicular damage. Swimming exercise had no significant role in reducing, or increasing the CC effects on the testis, despite having slightly improved the testis structure of the exercised rats without load. In conclusion, CC caused testis impairment, which could not be avoided by the swimming exercise.

Documentos Relacionados

• Efeitos do treinamento prévio em natação sobre a carcinogênese experimental do cólon em ratos Wistar
• Post-exercise ketosis in post-prandial exercise: effect of glucose and alanine ingestion in humans.
• Effect of swimming on reinnervation of rat skeletal muscle
• Metabolomics and Exercise: possibilities and perspectives
• INJURIES IN AEROBIC EXERCISE: CAUSES AND PREVENTIONS