Codon reiteration and the evolution of proteins.
AUTOR(ES)
Green, H
RESUMO
Sequence data banks have been searched for proteins possessing uninterrupted reiterations of any amino acid. Hydrophilic amino acids, and particularly glutamine, account for a large proportion of the longer reiterants. In the genes for these proteins, the most common reiterants are those that contain poly(CAG), even out-of-frame or, to a lesser degree, those that contain repeated doublets of CA, AG, or GC. The preferential generation of such reiterants requires that DNA strand-specific signals predispose to reiteration and thus to the extension of coding regions.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=43772Documentos Relacionados
- Molecular evolution, intracellular organization, and the quinary structure of proteins.
- Evolution-like selection of fast-folding model proteins.
- Early evolution of photosynthesis: clues from nitrogenase and chlorophyll iron proteins.
- Evidence for intron capture: an unusual path for the evolution of proteins.
- Evidence for intron capture: an unusual path for the evolution of proteins.
