Clinical and laboratorial features of oral candidiasis in HIV-positive patients
Spalanzani, Regiane Nogueira, Mattos, Karine, Marques, Luiza Inahe, Barros, Pedro Fernando Diniz, Pereira, Pamela Iruama Peres, Paniago, Anamaria Mello Miranda, Mendes, Rinaldo Poncio, Chang, Marilene Rodrigues
Rev. Soc. Bras. Med. Trop.
DATA DE PUBLICAÇÃO
Abstract INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.
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