Citrullination, a possible functional link between susceptibility genes and rheumatoid arthritis
AUTOR(ES)
Vossenaar, Erik R
FONTE
BioMed Central
RESUMO
Antibodies directed to citrullinated proteins (anti-cyclic citrullinated peptide) are highly specific for rheumatoid arthritis (RA). Recent data suggest that the antibodies may be involved in the disease process of RA and that several RA-associated genetic factors might be functionally linked to RA via modulation of the production of anti-cyclic citrullinated peptide antibodies or citrullinated antigens.
ACESSO AO ARTIGO
http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=400418Documentos Relacionados
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