Chronic meningitis by histoplasmosis: report of a child with acute myeloid leukemia
AUTOR(ES)
Pereira, G.H., Pádua, S.S., Park, M.V.F., Muller, R.P., Passos, R.M.A., Menezes, Y.
FONTE
Brazilian Journal of Infectious Diseases
DATA DE PUBLICAÇÃO
2008-12
RESUMO
Meningitis is a common evolution in progressive disseminated histoplasmosis in children, and is asymptomatic in many cases. In leukemia, the impaired of the T cells function can predispose to the disseminated form. The attributed mortality rate in this case is 20%-40% and the relapse rate is as high as 50%; therefore, prolonged treatment may be emphasized. We have described a child with acute myeloid leukemia (AML), that developed skin lesions and asymptomatic chronic meningitis, with a good evolution after prolonged treatment with amphotericin B deoxycholate followed by fluconazole.
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